Hi Mohan,
You can create a project in 7.20.1 and then upgrade it to 7.22.0.
I would consider using 7.22.1 or 7.22.2. When they do a subversion that usually means they fixed bugs, you can check this out in the release notes.
https://docs.mendix.com/releasenotes/desktop-modeler/7.22#7220